VThunter

Pig

Scientific Name: Sus scrofa domestica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Artiodactyla-> Suina-> Suidae-> Sus-> Sus scrofa

Mammalian orthoreovirus

Family: Reoviridae

Receptor: F11R

Receptor F11R information

Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0046	2021.04	10X Genomics	Lung	Normal	21981	Link
Vthunter_0070	2021.04	10X Genomics	Occipital	Normal	6829	Link
Vthunter_0071	2021.04	10X Genomics	Parietal	Normal	6162	Link
Vthunter_0072	2021.04	10X Genomics	Hypothalamus	Normal	7302	Link
Vthunter_0073	2021.04	10X Genomics	Temporal	Normal	3145	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_1013	2019.12	10X Genomics	Lung	Normal	7465	Link
Vthunter_1014	2019.12	10X Genomics	Lung	Normal	3987	Link

mRNA expression of F11R in human tissues [NCBI]

Expression: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]